Carfentanil | C24H30N2O3 | CID 62156 | Fentanyl and Carfentanil

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• Carfentanil or carfentanyl, sold under the brand name Wildnil, is an opioid analgesic that is used in veterinary medicine to anesthetize large animals such as elephants and bears.
• It is an analog of synthetic opioids like fentanyl.
• A unit of carfentanil is 100 times as potent as the same amount of fentanyl.
• Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutical which included Paul Janssen.
• It has a quantitative potency of approximately 10,000 times that of morphine and 100 times that of fentanyl.
• Its activities in humans start at about 1 microgram. Currently, sufentanil is approximately 10–20 times less potent (500 to 1000 times the efficacy of morphine per weight) is the maximum strength fentanyl analog for use in humans

Uses of carfentanyl:

• This is an analog of the popular synthetic opioid analgesic fentanyl and It is one of the most potent opioids known (also the most potent opioid used commercially).
• This chemical is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans.

What is the strongest opioid in the world?

• Codeine is only about 1/10th as powerful as morphine.
• Opioids more powerful than morphine include hydromorphone (Dilaudid) and oxymorphone (Opana).
• But the strongest opioid in community use is fentanyl which, in its intravenous form, is 70 to 100 times more potent than morphine

Side Effects:

• Absent or shallow breathing.
• Pinned or pinpoint pupils.
• Nausea or vomiting.
• Lethargy, dizziness, or sedation.
• Clammy, cold skin.
• Loss of consciousness.
• Absent or weak pulse and/or heart failure.

The risk of carfentanyl to human beings:

• This is a potent drug that is not legally sold.
• Its power is much more than other kinds of opioids.
• To be precise, we can say that it is 100 times stronger than fentanyl and 10,000 times stronger than morphine because of which extreme caution has to be exercised while taking this drug.

Impact:

• On the human body and the cerebrum, carfentanyl medication has a quick beginning which is hard to manage.
• The same is the case in the case of animals like the elephant also. When given to animals, they become unconscious.
• When this medication gets connected to the opioid receptors, there is a staggering of characteristic
• science that causes overdose indications.
• Owing to the dopamine spike, there is an intense feeling of euphoria along with drowsiness.
• Besides this, the capability of the neurotransmitters to decrease the neurotransmitter gets reduced because of the presence of this narcotic drug.

Impact of an overdose:

• An overdose of it can occur easily by just inhaling it or its absorption through the skin.
• You must keep naloxone handy as an immediate remedy for the overdose of this drug.
• Naloxone reduces the symptoms of the overdose until the doctor or the poison control center comes into action.
• This is the reason why it is good to use gloves and a mask to manage the medication.
• This forestalls odds of unintentional inward breath or retention through the skin by contacting it in uncovered hands.
• It is better if the persons who are qualified to handle it, tackle it, instead of the non-qualified ones.

Chemical Formula:

• Molar mass: 394.5006 g/mol
• CAS ID: 59708-52-0
• Formula: C24H30N2O3
• Biological half-life: 7.7 hrs
• Trade name: Wildnil
• ChemSpider ID: 55986

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